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Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms

For most neurodegenerative diseases the precise duration of an individual cell's death is unknown, which is an obstacle when counteractive measures are being considered. To address this, we used the rd1 mouse model for retinal neurodegeneration, characterized by phosphodiesterase-6 (PDE6) dysfu...

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Detalles Bibliográficos
Autores principales: Sahaboglu, A, Paquet-Durand, O, Dietter, J, Dengler, K, Bernhard-Kurz, S, Ekström, P AR, Hitzmann, B, Ueffing, M, Paquet-Durand, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593146/
https://www.ncbi.nlm.nih.gov/pubmed/23392176
http://dx.doi.org/10.1038/cddis.2013.12