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Inhibition of T Cell Protein Tyrosine Phosphatase Enhances Interleukin-18-Dependent Hematopoietic Stem Cell Expansion

The clinical application of hematopoietic progenitor cell-based therapies for the treatment of hematological diseases is hindered by current protocols, which are cumbersome and have limited efficacy to augment the progenitor cell pool. We report that inhibition of T-cell protein tyrosine phosphatase...

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Detalles Bibliográficos
Autores principales: Bourdeau, Annie, Trop, Sébastien, Doody, Karen M, Dumont, Daniel J, Tremblayef, Michel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593175/
https://www.ncbi.nlm.nih.gov/pubmed/23135963
http://dx.doi.org/10.1002/stem.1276