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Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1

Donor T cells directed at hematopoietic system-specific minor histocompatibility antigens (mHags) are considered important cellular tools to induce therapeutic graft-versus-tumor (GvT) effects with low risk of graft-versus-host disease after allogeneic stem cell transplantation. To enable the clinic...

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Detalles Bibliográficos
Autores principales: Oostvogels, R, Minnema, M C, van Elk, M, Spaapen, R M, te Raa, G D, Giovannone, B, Buijs, A, van Baarle, D, Kater, A P, Griffioen, M, Spierings, E, Lokhorst, H M, Mutis, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593180/
https://www.ncbi.nlm.nih.gov/pubmed/23079962
http://dx.doi.org/10.1038/leu.2012.277