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Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis

Many genetic variants associate with the risk of developing rheumatoid arthritis (RA); however, their functional roles are largely unknown. Here, we aimed to investigate whether the RA-associated serotonin receptor 2A (HTR2A) haplotype affects T-cell and monocyte functions. Patients with established...

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Detalles Bibliográficos
Autores principales: Snir, O, Hesselberg, E, Amoudruz, P, Klareskog, L, Zarea-Ganji, I, Catrina, A I, Padyukov, L, Malmström, V, Seddighzadeh, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593182/
https://www.ncbi.nlm.nih.gov/pubmed/23254357
http://dx.doi.org/10.1038/gene.2012.56