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Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis
Many genetic variants associate with the risk of developing rheumatoid arthritis (RA); however, their functional roles are largely unknown. Here, we aimed to investigate whether the RA-associated serotonin receptor 2A (HTR2A) haplotype affects T-cell and monocyte functions. Patients with established...
Autores principales: | Snir, O, Hesselberg, E, Amoudruz, P, Klareskog, L, Zarea-Ganji, I, Catrina, A I, Padyukov, L, Malmström, V, Seddighzadeh, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593182/ https://www.ncbi.nlm.nih.gov/pubmed/23254357 http://dx.doi.org/10.1038/gene.2012.56 |
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