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MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia

The haematopoietic system is prone to age-related disorders ranging from deficits in functional blood cells to the development of neoplastic states. Such neoplasms often involve recurrent cytogenetic abnormalities, among which a deletion in the long arm of chromosome 20 (del20q) is common in myeloid...

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Detalles Bibliográficos
Autores principales: Clarke, M, Dumon, S, Ward, C, Jäger, R, Freeman, S, Dawood, B, Sheriff, L, Lorvellec, M, Kralovics, R, Frampton, J, García, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593183/
https://www.ncbi.nlm.nih.gov/pubmed/22910183
http://dx.doi.org/10.1038/leu.2012.241