Mouse Lymphoblastic Leukemias Induced by Aberrant Prdm14 Expression Demonstrate Widespread Copy Number Alterations Also Found in Human ALL

Aberrant expression and activation of oncogenes in somatic cells has been associated with cancer initiation. Required for reacquisition of pluripotency in the developing germ cell, PRDM14 initiates lymphoblastic leukemia when misexpressed in murine bone marrow. Activation of pluripotency in somatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Simko, Stephen J., Voicu, Horatiu, Carofino, Brandi L., Justice, Monica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593237/
https://www.ncbi.nlm.nih.gov/pubmed/23487523
http://dx.doi.org/10.3390/cancers4041050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593237/
https://www.ncbi.nlm.nih.gov/pubmed/23487523
http://dx.doi.org/10.3390/cancers4041050

Ejemplares similares