Secondary mechanisms of diversification in the human antibody repertoire

V(D)J recombination and somatic hypermutation (SHM) are the primary mechanisms for diversification of the human antibody repertoire. These mechanisms allow for rapid humoral immune responses to a wide range of pathogenic challenges. V(D)J recombination efficiently generate a virtually limitless dive...

Descripción completa

Detalles Bibliográficos
Autores principales: Briney, Bryan S., Jr., James E. Crowe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593266/
https://www.ncbi.nlm.nih.gov/pubmed/23483107
http://dx.doi.org/10.3389/fimmu.2013.00042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593266/
https://www.ncbi.nlm.nih.gov/pubmed/23483107
http://dx.doi.org/10.3389/fimmu.2013.00042

Ejemplares similares