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In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen

BACKGROUND: As metastasis is the prime cause of death from malignancies, there is vibrant interest to discover options for the management of the different mechanistic steps of tumour spreading. Some approved pharmaceuticals exhibit activities against diseases they have not been developed for. In ord...

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Detalles Bibliográficos
Autores principales: Kretschy, N, Teichmann, M, Kopf, S, Atanasov, A G, Saiko, P, Vonach, C, Viola, K, Giessrigl, B, Huttary, N, Raab, I, Krieger, S, Jäger, W, Szekeres, T, Nijman, S M, Mikulits, W, Dirsch, V M, Dolznig, H, Grusch, M, Krupitza, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593542/
https://www.ncbi.nlm.nih.gov/pubmed/23299527
http://dx.doi.org/10.1038/bjc.2012.580