Novel Bruton’s tyrosine kinase inhibitors currently in development

Bruton’s tyrosine kinase (Btk) is intimately involved in multiple signal-transduction pathways regulating survival, activation, proliferation, and differentiation of B-lineage lymphoid cells. Btk is overexpressed and constitutively active in several B-lineage lymphoid malignancies. Btk has emerged a...

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Detalles Bibliográficos
Autores principales: D’Cruz, Osmond J, Uckun, Fatih M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594038/
https://www.ncbi.nlm.nih.gov/pubmed/23493945
http://dx.doi.org/10.2147/OTT.S33732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594038/
https://www.ncbi.nlm.nih.gov/pubmed/23493945
http://dx.doi.org/10.2147/OTT.S33732

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