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The Properties of Genome Conformation and Spatial Gene Interaction and Regulation Networks of Normal and Malignant Human Cell Types

The spatial conformation of a genome plays an important role in the long-range regulation of genome-wide gene expression and methylation, but has not been extensively studied due to lack of genome conformation data. The recently developed chromosome conformation capturing techniques such as the Hi-C...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Cao, Renzhi, Taylor, Kristen, Briley, Aaron, Caldwell, Charles, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594155/
https://www.ncbi.nlm.nih.gov/pubmed/23536826
http://dx.doi.org/10.1371/journal.pone.0058793