Steviol Reduces MDCK Cyst Formation and Growth by Inhibiting CFTR Channel Activity and Promoting Proteasome-Mediated CFTR Degradation

Cyst enlargement in polycystic kidney disease (PKD) involves cAMP-activated proliferation of cyst-lining epithelial cells and transepithelial fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. This study aimed to investigate an inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuajit, Chaowalit, Homvisasevongsa, Sureeporn, Chatsudthipong, Lisa, Soodvilai, Sunhapas, Muanprasat, Chatchai, Chatsudthipong, Varanuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594167/
https://www.ncbi.nlm.nih.gov/pubmed/23536832
http://dx.doi.org/10.1371/journal.pone.0058871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594167/
https://www.ncbi.nlm.nih.gov/pubmed/23536832
http://dx.doi.org/10.1371/journal.pone.0058871

Ejemplares similares