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The N Terminus of Orf Virus-Encoded Protein 002 Inhibits Acetylation of NF-κB p65 by Preventing Ser(276) Phosphorylation

Orf virus-encoded protein 002 (ORFV002) inhibits NF-κB signaling pathway by decreasing the acetylation of NF-κB-p65 through interference of NF-κB p65′s association with NF-κB p300. However, the precise mechanism of how ORFV002 interferes with the NF-κB p65/p300 association is still unknown. Due to s...

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Detalles Bibliográficos
Autores principales: Ning, Zhangyong, Zheng, Zewei, Hao, Wenbo, Duan, Chaohui, Li, Wei, Wang, Yuanyuan, Li, Ming, Luo, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594181/
https://www.ncbi.nlm.nih.gov/pubmed/23536830
http://dx.doi.org/10.1371/journal.pone.0058854