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Cellular Catabolism of the Iron-Regulatory Peptide Hormone Hepcidin
Hepcidin, a 25-amino acid peptide hormone, is the principal regulator of plasma iron concentrations. Hepcidin binding to its receptor, the iron exporter ferroportin, induces ferroportin internalization and degradation, thus blocking iron efflux from cells into plasma. The aim of this study was to ch...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594189/ https://www.ncbi.nlm.nih.gov/pubmed/23536837 http://dx.doi.org/10.1371/journal.pone.0058934 |