Urokinase Plasminogen Activator Induces Pro-Fibrotic/M2 Phenotype in Murine Cardiac Macrophages

OBJECTIVE: Inflammation and fibrosis are intertwined in multiple disease processes. We have previously found that over-expression of urokinase plasminogen activator in macrophages induces spontaneous macrophage accumulation and fibrosis specific to the heart in mice. Understanding the relationship b...

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Detalles Bibliográficos
Autores principales: Meznarich, Jessica, Malchodi, Laura, Helterline, Deri, Ramsey, Stephen A., Bertko, Kate, Plummer, Tabitha, Plawman, Abigail, Gold, Elizabeth, Stempien-Otero, April
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594198/
https://www.ncbi.nlm.nih.gov/pubmed/23536772
http://dx.doi.org/10.1371/journal.pone.0057837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594198/
https://www.ncbi.nlm.nih.gov/pubmed/23536772
http://dx.doi.org/10.1371/journal.pone.0057837

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