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A Novel 3D Fibril Force Assay Implicates Src in Tumor Cell Force Generation in Collagen Networks

New insight into the biomechanics of cancer cell motility in 3D extracellular matrix (ECM) environments would significantly enhance our understanding of aggressive cancers and help identify new targets for intervention. While several methods for measuring the forces involved in cell-matrix interacti...

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Detalles Bibliográficos
Autores principales: Polackwich, Robert J., Koch, Daniel, Arevalo, Richard, Miermont, Anne M., Jee, Kathleen J., Lazar, John, Urbach, Jeffrey, Mueller, Susette C., McAllister, Ryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594227/
https://www.ncbi.nlm.nih.gov/pubmed/23536784
http://dx.doi.org/10.1371/journal.pone.0058138