Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G₀-phase human cells

We recently reported that homologous chromosomes make contact at the sites of double-strand breaks (DSBs) induced by ionizing radiation (IR) and the restriction endonuclease I-PpoI in G₀/G₁-phase somatic human cells. The contact involves short segments of homologous chromosomes and is centered on a...

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Detalles Bibliográficos
Autores principales: Gandhi, Manoj, Evdokimova, Viktoria N., Cuenco, Karen T., Bakkenist, Christopher J., Nikiforov, Yuri E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594255/
https://www.ncbi.nlm.nih.gov/pubmed/23370393
http://dx.doi.org/10.4161/cc.23754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594255/
https://www.ncbi.nlm.nih.gov/pubmed/23370393
http://dx.doi.org/10.4161/cc.23754

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