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Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G₀-phase human cells
We recently reported that homologous chromosomes make contact at the sites of double-strand breaks (DSBs) induced by ionizing radiation (IR) and the restriction endonuclease I-PpoI in G₀/G₁-phase somatic human cells. The contact involves short segments of homologous chromosomes and is centered on a...
Autores principales: | Gandhi, Manoj, Evdokimova, Viktoria N., Cuenco, Karen T., Bakkenist, Christopher J., Nikiforov, Yuri E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594255/ https://www.ncbi.nlm.nih.gov/pubmed/23370393 http://dx.doi.org/10.4161/cc.23754 |
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