A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3

Activation of a cellular senescence program is a common response to prolonged oncogene activation or tumor suppressor loss, providing a physiological mechanism for tumor suppression in premalignant cells. The link between senescence and tumor suppression supports the hypothesis that a loss-of-functi...

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Detalles Bibliográficos
Autores principales: Lahtela, Jenni, Corson, Laura B., Hemmes, Annabrita, Brauer, Matthew J., Koopal, Sonja, Lee, James, Hunsaker, Thomas L., Jackson, Peter K., Verschuren, Emmy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594263/
https://www.ncbi.nlm.nih.gov/pubmed/23324396
http://dx.doi.org/10.4161/cc.23515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594263/
https://www.ncbi.nlm.nih.gov/pubmed/23324396
http://dx.doi.org/10.4161/cc.23515

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