ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage

Previous work has established that heterogeneous nuclear ribonucleoprotein K (hnRNP K) is stabilized in an ATM-dependent manner in response to DNA damage and acts as a cofactor for p53-mediated transcription. Here, we show that in response to DNA damage caused by ionizing radiation, hnRNP K is phosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Moumen, Abdeladim, Magill, Christine, Dry, Katherine L., Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594270/
https://www.ncbi.nlm.nih.gov/pubmed/23343766
http://dx.doi.org/10.4161/cc.23592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594270/
https://www.ncbi.nlm.nih.gov/pubmed/23343766
http://dx.doi.org/10.4161/cc.23592

Ejemplares similares