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ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage

Previous work has established that heterogeneous nuclear ribonucleoprotein K (hnRNP K) is stabilized in an ATM-dependent manner in response to DNA damage and acts as a cofactor for p53-mediated transcription. Here, we show that in response to DNA damage caused by ionizing radiation, hnRNP K is phosp...

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Detalles Bibliográficos
Autores principales:	Moumen, Abdeladim, Magill, Christine, Dry, Katherine L., Jackson, Stephen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594270/ https://www.ncbi.nlm.nih.gov/pubmed/23343766 http://dx.doi.org/10.4161/cc.23592

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