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d(GGGT)(4) and r(GGGU)(4) are both HIV-1 inhibitors and interleukin-6 receptor aptamers
Aptamers are oligonucleotides that bind targets with high specificity and affinity. They have become important tools for biosensing, target detection, drug delivery and therapy. We selected the quadruplex-forming 16-mer DNA aptamer AID-1 [d(GGGT)(4)] with affinity for the interleukin-6 receptor (IL-...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594281/ https://www.ncbi.nlm.nih.gov/pubmed/23235494 http://dx.doi.org/10.4161/rna.22951 |