IL-17A Modulates Oxidant Stress-Induced Airway Hyperresponsiveness but Not Emphysema

IL-17A induces the release of pro-inflammatory cytokines and of reactive oxygen species which could lead to neutrophilic inflammation. We determined the role of IL-17 receptor (IL-17R) signalling in oxidant-induced lung emphysema and airway hyperresponsiveness. IL-17R(−/−) and wild-type C57/BL6 mice...

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Detalles Bibliográficos
Autores principales: Pinart, Mariona, Zhang, Min, Li, Feng, Hussain, Farhana, Zhu, Jie, Wiegman, Coen, Ryffel, Bernard, Chung, Kian Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594315/
https://www.ncbi.nlm.nih.gov/pubmed/23505509
http://dx.doi.org/10.1371/journal.pone.0058452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594315/
https://www.ncbi.nlm.nih.gov/pubmed/23505509
http://dx.doi.org/10.1371/journal.pone.0058452

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