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High Efficiency Diffusion Molecular Retention Tumor Targeting

Here we introduce diffusion molecular retention (DMR) tumor targeting, a technique that employs PEG-fluorochrome shielded probes that, after a peritumoral (PT) injection, undergo slow vascular uptake and extensive interstitial diffusion, with tumor retention only through integrin molecular recogniti...

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Detalles Bibliográficos
Autores principales: Guo, Yanyan, Yuan, Hushan, Cho, Hoonsung, Kuruppu, Darshini, Jokivarsi, Kimmo, Agarwal, Aayush, Shah, Khalid, Josephson, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594319/
https://www.ncbi.nlm.nih.gov/pubmed/23505478
http://dx.doi.org/10.1371/journal.pone.0058290