Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury

The mechanisms which regulate HSC regeneration following myelosuppressive injury are not well understood. We identified epidermal growth factor (EGF) to be highly enriched in the bone marrow (BM) serum of mice bearing deletion of Bak and Bax in Tie2(+) cells (Tie2Cre;Bak1(−/−);Bax(fl/−) mice), which...

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Detalles Bibliográficos
Autores principales: Doan, Phuong L., Himburg, Heather A., Helms, Katherine, Russell, J. Lauren, Fixsen, Emma, Quarmyne, Mamle, Harris, Jeffrey R., Deoliviera, Divino, Sullivan, Julie M., Chao, Nelson J., Kirsch, David G., Chute, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594347/
https://www.ncbi.nlm.nih.gov/pubmed/23377280
http://dx.doi.org/10.1038/nm.3070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594347/
https://www.ncbi.nlm.nih.gov/pubmed/23377280
http://dx.doi.org/10.1038/nm.3070

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