Allelic mRNA expression imbalance in C-type lectins reveals a frequent regulatory SNP in the human surfactant protein A (SP-A) gene

Genetic variation in C-type lectins influences infectious disease susceptibility but remains poorly understood. We employed allelic mRNA expression imbalance (AEI) technology for SP-A1, SP-A2, SP-D, DC-SIGN, MRC1, and Dectin-1, expressed in human macrophages and/or lung tissues. Frequent AEI, an ind...

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Detalles Bibliográficos
Autores principales: Azad, Abul K., Curtis, Amanda, Papp, Audrey, Webb, Amy, Knoell, Daren, Sadee, Wolfgang, Schlesinger, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594410/
https://www.ncbi.nlm.nih.gov/pubmed/23328842
http://dx.doi.org/10.1038/gene.2012.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594410/
https://www.ncbi.nlm.nih.gov/pubmed/23328842
http://dx.doi.org/10.1038/gene.2012.61

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