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An Influenza Virus M2 Protein Specific Chimeric Antigen Receptor Modulates Influenza A/WSN/33 H1N1 Infection In Vivo

A potential target for the development of universal vaccine strategies against Influenza A is the M2 protein – a membrane protein with a highly conserved extracellular domain. In this study we developed engineered T-cell receptors, by fusing M2-specific antibody sequences with T-cell receptor transm...

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Detalles Bibliográficos
Autores principales: Talbot, Simon J, Blair, Natalie F, McGill, Niolette, Ligertwood, Yvonne, Dutia, Bernadette M, Johannessen, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594705/
https://www.ncbi.nlm.nih.gov/pubmed/23493233
http://dx.doi.org/10.2174/1874357901307010028