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Suppression of TLR Signaling by Targeting TIR domain-Containing Proteins

Toll-like receptors (TLRs) recognize molecules specific to pathogens and endogenous danger signals. Binding of agonists to the ectodomain of the receptor initiates TLR activation and is followed by the association of receptor cytosolic Toll/Interleukin-1 receptor (TIR) domains with TIR domains of ad...

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Detalles Bibliográficos
Autores principales: Fekonja, Ota, Avbelj, Monika, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594740/
https://www.ncbi.nlm.nih.gov/pubmed/23305364
http://dx.doi.org/10.2174/138920312804871148