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SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion

The S2 domain of the coronavirus spike (S) protein is known to be responsible for mediating membrane fusion. In addition to a well-recognized cleavage site at the S1–S2 boundary, a second proteolytic cleavage site has been identified in the severe acute respiratory syndrome coronavirus (SARS-CoV) S2...

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Detalles Bibliográficos
Autores principales: Madu, Ikenna G., Belouzard, Sandrine, Whittaker, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594805/
https://www.ncbi.nlm.nih.gov/pubmed/19717178
http://dx.doi.org/10.1016/j.virol.2009.07.038