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Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression

Evidence that lipocalin 2 (LCN2) is oncogenic has grown in recent years and comes from both animal models and expression analysis from a variety of human cancers. In the intestine, LCN2 is overexpressed in colitis patients and its overexpression is a negative prognostic indicator in colorectal cance...

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Detalles Bibliográficos
Autores principales: Reilly, P T, Teo, W L, Low, M J, Amoyo-Brion, A A, Dominguez-Brauer, C, Elia, A J, Berger, T, Greicius, G, Pettersson, S, Mak, T W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594828/
https://www.ncbi.nlm.nih.gov/pubmed/22614012
http://dx.doi.org/10.1038/onc.2012.159