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The pharmacokinetics and safety of an intraoperative bupivacaine-collagen implant (XaraColl(®)) for postoperative analgesia in women following total abdominal hysterectomy

BACKGROUND: XaraColl(®), a collagen-based intraoperative implant that delivers bupivacaine to the site of surgical trauma, is under development for postoperative analgesia. We examined the pharmacokinetics, safety and efficacy of XaraColl following implantation in women undergoing total abdominal hy...

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Detalles Bibliográficos
Autores principales: Cusack, Susan L, Reginald, Philip, Hemsen, Lisa, Umerah, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594918/
https://www.ncbi.nlm.nih.gov/pubmed/23503706
http://dx.doi.org/10.2147/JPR.S40976