Using a Fragment-Based Approach To Target Protein–Protein Interactions

The ability to identify inhibitors of protein–protein interactions represents a major challenge in modern drug discovery and in the development of tools for chemical biology. In recent years, fragment-based approaches have emerged as a new methodology in drug discovery; however, few examples of smal...

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Detalles Bibliográficos
Autores principales: Scott, Duncan E, Ehebauer, Matthias T, Pukala, Tara, Marsh, May, Blundell, Tom L, Venkitaraman, Ashok R, Abell, Chris, Hyvönen, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594973/
https://www.ncbi.nlm.nih.gov/pubmed/23344974
http://dx.doi.org/10.1002/cbic.201200521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594973/
https://www.ncbi.nlm.nih.gov/pubmed/23344974
http://dx.doi.org/10.1002/cbic.201200521

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