A Triple-Transgenic Immunotolerant Mouse Model

Avoiding unwanted immunogenicity is of key importance in the development of therapeutic drug proteins. Animal models are of less predictive value because most of the drug proteins are recognized as foreign proteins. However, different methods have been developed to obtain immunotolerant animal model...

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Detalles Bibliográficos
Autores principales: Brenden, Nina, Madeyski-Bengtson, Katja, Martinsson, Klara, Svärd, Rebecka, Albery-Larsdotter, Sara, Granath, Britta, Lundgren, Hanna, Lövgren, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:
Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594975/
https://www.ncbi.nlm.nih.gov/pubmed/23316010
http://dx.doi.org/10.1002/jps.23447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594975/
https://www.ncbi.nlm.nih.gov/pubmed/23316010
http://dx.doi.org/10.1002/jps.23447

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