Intraspecific Evolution of Human RCCX Copy Number Variation Traced by Haplotypes of the CYP21A2 Gene

The RCCX region is a complex, multiallelic, tandem copy number variation (CNV). Two complete genes, complement component 4 (C4) and steroid 21-hydroxylase (CYP21A2, formerly CYP21B), reside in its variable region. RCCX is prone to nonallelic homologous recombination (NAHR) such as unequal crossover,...

Descripción completa

Detalles Bibliográficos
Autores principales: Bánlaki, Zsófia, Szabó, Julianna Anna, Szilágyi, Ágnes, Patócs, Attila, Prohászka, Zoltán, Füst, George, Doleschall, Márton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595039/
https://www.ncbi.nlm.nih.gov/pubmed/23241443
http://dx.doi.org/10.1093/gbe/evs121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595039/
https://www.ncbi.nlm.nih.gov/pubmed/23241443
http://dx.doi.org/10.1093/gbe/evs121

Ejemplares similares