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Beyond BLASTing: Tertiary and Quaternary Structure Analysis Helps Identify Major Vault Proteins

We examine the advantages of going beyond sequence similarity and use both protein three-dimensional (3D) structure prediction and then quaternary structure (docking) of inferred 3D structures to help evaluate whether comparable sequences can fold into homologous structures with sufficient lateral a...

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Detalles Bibliográficos
Autores principales: Daly, Toni K., Sutherland-Smith, Andrew J., Penny, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595041/
https://www.ncbi.nlm.nih.gov/pubmed/23275487
http://dx.doi.org/10.1093/gbe/evs135