Impaired selection of IgA and intestinal dysbiosis associated with PD-1-deficiency

A major function of immunoglobulin A (IgA) is to maintain balanced bacterial communities in the gut. We have previously shown that diversification of IgA upon somatic hypermutation (SHM) is critical for IgA function yet the principles governing the selection of IgA in the gut have remained elusive....

Descripción completa

Detalles Bibliográficos
Autores principales: Maruya, Mikako, Kawamoto, Shimpei, Kato, Lucia M., Fagarasan, Sidonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595078/
https://www.ncbi.nlm.nih.gov/pubmed/23333864
http://dx.doi.org/10.4161/gmic.23595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595078/
https://www.ncbi.nlm.nih.gov/pubmed/23333864
http://dx.doi.org/10.4161/gmic.23595

Ejemplares similares