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Impaired selection of IgA and intestinal dysbiosis associated with PD-1-deficiency
A major function of immunoglobulin A (IgA) is to maintain balanced bacterial communities in the gut. We have previously shown that diversification of IgA upon somatic hypermutation (SHM) is critical for IgA function yet the principles governing the selection of IgA in the gut have remained elusive....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595078/ https://www.ncbi.nlm.nih.gov/pubmed/23333864 http://dx.doi.org/10.4161/gmic.23595 |