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Phosphocitrate Is Potentially a Disease-Modifying Drug for Noncrystal-Associated Osteoarthritis

Phosphocitrate (PC), a calcification inhibitor, inhibits the development of crystal-associated osteoarthritis (OA) in Hartley guinea pigs. However, the molecular mechanisms underlying its disease-modifying effect remain elusive. This study sought to test the hypothesis that PC has calcium crystal-in...

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Detalles Bibliográficos
Autores principales: Sun, Yubo, Mauerhan, David R., Franklin, Atiya M., Norton, James, Hanley, Edward N., Gruber, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595112/
https://www.ncbi.nlm.nih.gov/pubmed/23555081
http://dx.doi.org/10.1155/2013/326267