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Drosophila Bestrophin-1 Currents Are Regulated by Phosphorylation via a CaMKII Dependent Mechanism

Cell swelling induced by hypo-osmotic stress results in activation of volume-regulated anion channels (VRAC) that drive a compensatory regulatory volume decrease. We have previously shown that the Best1 gene in Drosophila encodes a VRAC that is also activated by increases in intracellular Ca(2+). Th...

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Detalles Bibliográficos
Autores principales: Duran, Charity, Chien, Li-Ting, Hartzell, H. Criss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595206/
https://www.ncbi.nlm.nih.gov/pubmed/23554946
http://dx.doi.org/10.1371/journal.pone.0058875