Cargando…

Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals

Hedgehog (Hh) proteins control animal development and tissue homeostasis. They activate gene expression by regulating processing, stability, and activation of Gli/Cubitus interruptus (Ci) transcription factors. Hh proteins are secreted and spread through tissue, despite becoming covalently linked to...

Descripción completa

Detalles Bibliográficos
Autores principales: Palm, Wilhelm, Swierczynska, Marta M., Kumari, Veena, Ehrhart-Bornstein, Monika, Bornstein, Stefan R., Eaton, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595218/
https://www.ncbi.nlm.nih.gov/pubmed/23554573
http://dx.doi.org/10.1371/journal.pbio.1001505