Cargando…
Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals
Hedgehog (Hh) proteins control animal development and tissue homeostasis. They activate gene expression by regulating processing, stability, and activation of Gli/Cubitus interruptus (Ci) transcription factors. Hh proteins are secreted and spread through tissue, despite becoming covalently linked to...
Autores principales: | Palm, Wilhelm, Swierczynska, Marta M., Kumari, Veena, Ehrhart-Bornstein, Monika, Bornstein, Stefan R., Eaton, Suzanne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595218/ https://www.ncbi.nlm.nih.gov/pubmed/23554573 http://dx.doi.org/10.1371/journal.pbio.1001505 |
Ejemplares similares
-
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling
por: Qi, Xiaofeng, et al.
Publicado: (2020) -
Dual roles of the sterol recognition region in Hedgehog protein modification
por: Purohit, Rahul, et al.
Publicado: (2020) -
Structural basis of sterol recognition by human hedgehog receptor PTCH1
por: Qi, Chao, et al.
Publicado: (2019) -
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids
por: Lo, Megan, et al.
Publicado: (2022) -
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway
por: Findakly, Sarah, et al.
Publicado: (2020)