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Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo

Here we have characterized perthamide C, a cyclopeptide from a Solomon Lithistid sponge Theonella swinhoei, which displays an anti-inflammatory/immunomodulatory activity. The study has been performed using the carragenan-induced mouse paw edema that displays an early (0–6 h) and a late phase (24–96...

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Detalles Bibliográficos
Autores principales: Bucci, Mariarosaria, Cantalupo, Anna, Vellecco, Valentina, Panza, Elisabetta, Monti, Maria Chiara, Zampella, Angela, Ianaro, Angela, Cirino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595234/
https://www.ncbi.nlm.nih.gov/pubmed/23554869
http://dx.doi.org/10.1371/journal.pone.0057801