A Dictyostelium Secreted Factor Requires a PTEN-Like Phosphatase to Slow Proliferation and Induce Chemorepulsion

In Dictyostelium discoideum, AprA and CfaD are secreted proteins that inhibit cell proliferation. We found that the proliferation of cells lacking CnrN, a phosphatase and tensin homolog (PTEN)-like phosphatase, is not inhibited by exogenous AprA and is increased by exogenous CfaD. The expression of...

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Detalles Bibliográficos
Autores principales: Herlihy, Sarah E., Tang, Yitai, Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595242/
https://www.ncbi.nlm.nih.gov/pubmed/23555023
http://dx.doi.org/10.1371/journal.pone.0059365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595242/
https://www.ncbi.nlm.nih.gov/pubmed/23555023
http://dx.doi.org/10.1371/journal.pone.0059365

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