Proteasome Activity Influences UV-Mediated Subnuclear Localization Changes of NPM

UV damage activates cellular stress signaling pathways, causes DNA helix distortions and inhibits transcription by RNA polymerases I and II. In particular, the nucleolus, which is the site of RNA polymerase I transcription and ribosome biogenesis, disintegrates following UV damage. The disintegratio...

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Detalles Bibliográficos
Autores principales: Moore, Henna M., Bai, Baoyan, Matilainen, Olli, Colis, Laureen, Peltonen, Karita, Laiho, Marikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595268/
https://www.ncbi.nlm.nih.gov/pubmed/23554979
http://dx.doi.org/10.1371/journal.pone.0059096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595268/
https://www.ncbi.nlm.nih.gov/pubmed/23554979
http://dx.doi.org/10.1371/journal.pone.0059096

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