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Ex Vivo Modeling of Chemical Synergy in Prenatal Kidney Cystogenesis

Cyclic adenosine monophosphate (cAMP) drives genetic polycystic kidney disease (PKD) cystogenesis. Yet within certain PKD families, striking differences in disease severity exist between affected individuals, and genomic and/or environmental modifying factors have been evoked to explain these observ...

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Detalles Bibliográficos
Autores principales: Anders, Corina, Ashton, Nick, Ranjzad, Parisa, Dilworth, Mark R., Woolf, Adrian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595278/
https://www.ncbi.nlm.nih.gov/pubmed/23554868
http://dx.doi.org/10.1371/journal.pone.0057797