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Functional Implications of MicroRNA-215 in TGF-β1-Induced Phenotypic Transition of Mesangial Cells by Targeting CTNNBIP1

Mesangial cell (MC) phenotypic transition is crucial for the progression of diabetic nephropathy. A major stimulus mediating high glucose-induced MC phenotypic transition is TGF-β1. Our current study focuses on microRNA-215 (miR-215) and investigates its role in TGF-β1-mediated MC phenotypic transit...

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Detalles Bibliográficos
Autores principales: Mu, Jiao, Pang, Qi, Guo, Yan-Hong, Chen, Ji-Gang, Zeng, Wei, Huang, Yong-Jun, Zhang, Jun, Feng, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595285/
https://www.ncbi.nlm.nih.gov/pubmed/23554908
http://dx.doi.org/10.1371/journal.pone.0058622