Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts

BACKGROUND: Porphyromonas gingivalis is a major pathogen of periodontal disease that affects a majority of adults worldwide. Increasing evidence shows that periodontal disease is linked to various systemic diseases like diabetes and cardiovascular disease, by contributing to increased systemic level...

Descripción completa

Detalles Bibliográficos
Autores principales: Herath, Thanuja D. K., Darveau, Richard P., Seneviratne, Chaminda J., Wang, Cun-Yu, Wang, Yu, Jin, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595299/
https://www.ncbi.nlm.nih.gov/pubmed/23554896
http://dx.doi.org/10.1371/journal.pone.0058496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595299/
https://www.ncbi.nlm.nih.gov/pubmed/23554896
http://dx.doi.org/10.1371/journal.pone.0058496

Ejemplares similares