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Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts

BACKGROUND: Porphyromonas gingivalis is a major pathogen of periodontal disease that affects a majority of adults worldwide. Increasing evidence shows that periodontal disease is linked to various systemic diseases like diabetes and cardiovascular disease, by contributing to increased systemic level...

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Detalles Bibliográficos
Autores principales:	Herath, Thanuja D. K., Darveau, Richard P., Seneviratne, Chaminda J., Wang, Cun-Yu, Wang, Yu, Jin, Lijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595299/ https://www.ncbi.nlm.nih.gov/pubmed/23554896 http://dx.doi.org/10.1371/journal.pone.0058496

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