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Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells

Breast cancer can be classified into different molecular subtypes with varying clinical and pathological characteristics. The basal-like breast cancer subtype represents one of the most aggressive and lethal types of breast cancer, and due to poor mechanistic understanding, it lacks targeted therapy...

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Detalles Bibliográficos
Autores principales: Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595307/
https://www.ncbi.nlm.nih.gov/pubmed/23291982
http://dx.doi.org/10.4161/cbt.23297