Cargando…
Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells
Breast cancer can be classified into different molecular subtypes with varying clinical and pathological characteristics. The basal-like breast cancer subtype represents one of the most aggressive and lethal types of breast cancer, and due to poor mechanistic understanding, it lacks targeted therapy...
Autores principales: | Pires, Maira M., Hopkins, Benjamin D., Saal, Lao H., Parsons, Ramon E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595307/ https://www.ncbi.nlm.nih.gov/pubmed/23291982 http://dx.doi.org/10.4161/cbt.23297 |
Ejemplares similares
-
Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer
por: She, Qing-Bai, et al.
Publicado: (2016) -
PTEN and NEDD4 in Human Breast Carcinoma
por: Chen, Yilun, et al.
Publicado: (2015) -
Regulation of mammary epithelial architecture by PTEN
por: Lim, JC, et al.
Publicado: (2010) -
Pten in Stromal Fibroblasts Suppresses Mammary Epithelial Tumors
por: Trimboli, Anthony J., et al.
Publicado: (2009) -
Stromal PTEN determines mammary epithelial response to radiotherapy
por: Sizemore, Gina M., et al.
Publicado: (2018)